Theron and MacFarlane previously worked together on his feature film A MILLION WAYS TO DIE IN THE WEST.
From MacFarlane and Jon Favreau, The Orville is a one-hour sci-fi series that follows a down-on-his-luck officer (MacFarlane) who commands the titular U.S.S. Orville. Things become a tad complicated when his ex-wife (Adrianne Palicki) is assigned as the ship’s First Officer.
Theron is executive producing two TV shows for Netflix, the recently canceled Girlboss and the upcoming Mindhunter, but was last seen on the small screen back in 2005, when she did an arc on Arrested Development.
The Orville premieres Sunday, September 10 at 8 p.m. ET on Fox.