Steven Mackintosh, Zawe Ashton and Royce Pierreson have also joined the six-part miniseries, which is now filming.
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Dakota Johnson co-stars as a kind nurse who helps LaBeouf get a young man with Down syndrome (newcomer Zachary Gottsagen) to a professional wresting school in rural North Carolina.
Toni Collette and Molly Shannon are set to star in the ensemble comedy Fun Mom Dinner alongside Katie Aselton from The League and Bridget Everett from Trainwreck.
Star Wars: The Force Awakens star Domhnall Gleeson, Christina Applegate, and Thomas Haden Church are starring in Crash Pad, a rom-com from Black List scribe Jeremy Catalino.